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Surviving the "Valley of Death": A Drug Discovery Horror Story (That Doesn't Have to End Badly)
It’s late. The lab is quiet, except for that one dataset everyone’s staring at. You’ve just seen something real. A molecule that’s hitting hard across cancer cell line models. Clean biology. Strong IC50 values. Even the in vivo data looks promising. For a moment, it feels like this might be it. Fast-forward two years. The program is nowhere. No clear path forward. No partner. No momentum. Just another asset that couldn’t cross the line, buried in the infamous “Valley of Death
Madhavi Mulay
Apr 82 min read
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